Biomarkers suggest link between OA, stiff landing after ACL reconstruction

By Jordana Bieze Foster Knee stiffness during landing in patients who have had anterior cruciate ligament (ACL) reconstruction is associated with biomarkers for cartilage degeneration, suggesting that a stiff landing technique may increase the risk of knee osteoarthritis (OA) in these patients, according to research presented in May at the ACSM meeting. In 22 patients who were, on average, six months removed from ACL reconstruction, investigators from the University of Florida in Gainesville analyzed single-leg forward drop-landing mechanics and the urine concentration of two biomarkers for cartilage degeneration. Knee stiffness was significantly associated with biomarker uC2C, while an association with biomarker uCTX-II approached significance

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Biomarkers suggest link between OA, stiff landing after ACL reconstruction

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