Diabetic Foot Blog

What to Ask? What to Look For? What to Do? 3 Minute Diabetic Foot Exam: Infographic @bio5 @UAhealthnet @uazsurgery

December 20, 2014

What to ask?

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Surprising: Better relations with Cuba might help Americans with #Diabetes and Wounds

December 18, 2014

Cuban stamps issued in 2012 commemorating the fifth anniversary of Heberprot and the 100,000 patients worldwide that had been treated with the anti-amputation medication. The number is now estimated at at more than 170,000

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Launching new study to reverse Type 2 Diabetes – Virgin.com

December 16, 2014

Launching new study to reverse Type 2 Diabetes : Here’s to our colleague Prof. Nigel Unwin and Sir Richard Branson for launching this bold initiative: The Barbados Diabetes Reversal Study (BDRS) aimed at the heart of the Diabetes epidemic in the Western Hemisphere.

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Minocycline and the Treatment of Multidrug-Resistant Acinetobacter baumannii

December 15, 2014

When most of us think about minocycline it is for the oral treatment of gram positive infection, in particular MRSA.  In fact, the drug is effective against multidrug resistant gram negative organisms, including Acinetobacter baumannii (AB). This point was driven home to me recently when I saw that my favorite ID journal Clinical Infectious Diseases just published a supplement on the topic.  Here is the link to the Table of Contents.  All of the articles are available as free full text and can be downloaded from this link: http://cid.oxfordjournals.org/content/59/suppl_6.toc#MINOCYCLINEFORTHETREATMENTOFMULTIDRUG-RESISTANTACINETOBACTERBAUMANNII This supplement was sponsored by The Medicines Company www.themedicinescompany.com who are now marketing an IV formulation of minocycline for this purpose so take that into account while reading the papers. That being said, both of the Guest Editors, Debra Goff, PharmD and Keith Kaye MD, MPH are top quality, fair balanced researchers and authors

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The Press Reporting of ID and Antibiotics

December 12, 2014

USA Today ran an interesting story yesterday about a 19 year old woman given an antibiotic by a friend for a “sore throat” who developed Stevens Johnson Syndrome.  This is a terrible incident and my thoughts and prayers go out to the young woman and her family.  What bothered me however was the way in which USA Today reported it.  Here is the link: http://www.usatoday.com/story/news/nation/2014/12/11/teen-antibiotic-burn-inside-out/20249585/ Yes, it was reported that there was a teen who took an antibiotic making her “Burn From the Inside Out” .  Talk about sensationalism!  It appears that they got that phrase from a physician they contacted.  Now, I’m not questioning the accuracy of that description but it is the use of it in the headline that makes me shake my head.  CNN reported the same story with a more sedate headline: “ A friend gave her an antibiotic; now she’s fighting for her life” http://www.cnn.com/2014/12/10/health/california-antibiotic-allergic-reaction/index.html?hpt=hp_t2 This just got me thinking about other ways in which the lay press reports on infectious diseases and antibiotics.  How many articles have been written on “Super Bugs”?  What ARE “super bugs” anyway?  In one story they may be MRSA, in another CREs.  What about “flesh eating bacteria”?  Some of us remember back about 15 years ago when this term first became popularly used in the press.  It referred to a series of cases of Group A Streptococcal necrotizing fasciitis.  This was hardly a new infection, even back then.  It has probably been around since the beginning of time but boy did they run with it.  Then, within the past few years “flesh eating bacteria” somehow morphed from Group A Strep to MRSA.  Which is it?  Is it both?  I guess. Finally, since I have been asked frequently, let’s look at Ebola.  Now I am not, and have never claimed to be an expert on viral diseases in general and Ebola in specific.  I have never seen or treated a case and hope to never come across it.  However, just a few weeks ago you could not turn on the TV, pick up a newspaper or magazine and not read about this terrible disease.  In fact, Time Magazine, rightly IMHO, just named those who fight Ebola as their “People of the Year”.  However, let’s put this into perspective.  To the best of my knowledge there were only TWO cases actually contracted in the US and both of those were health care workers directly treating the first unfortunate patient in Dallas.  That did not stop the news sources from rolling out expert after expert about how this disease could potentially spread here in the States, or maybe not.  People were freaking out.   For the first time in all my years of travel I was seeing folks wearing surgical masks on airplanes and taking out sanitizing wipes to treat the airplane seats and trays before sitting down (actually, probably not a bad idea!).  But, as the old saying goes, “today’s news is tomorrow’s fish wrapper”. Other than the Time story, I don’t think I have seen anything about the disease in a few weeks.

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Medscape Interview about Diabetic Foot Osteomyelitis

December 8, 2014

Just over a week ago my good friend and colleague in lower extremity ID, Mark Kosinski, DPM, FIDSA and I were interviewed by Miriam Tucker, a reporter for Medscape, about a recent paper that compared 6 weeks vs 12 weeks of antibiotic therapy for DFO that did not undergo surgical debridement.  The impetus for this interview was a study published in Diabetes Care by Tone, et.al.  Here are links to the PubMed abstract for that paper, and the original interview on Medscape along with a link to David Armstrong’s excellent “diabeticfootonline” blog where, with his permission and my thanks to him, I am cutting and pasting his reporting of this below. Although the article is a bit longer than my usual posting, I think it is worth reading as both Mark and I discuss what is unique and interesting about this excellent study

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Study: Rescue of Diabetes-related Impairment of Ischemia-mediated Neovascularization With Fenofibrate?

December 2, 2014

Abstract 14774: Rescue of Diabetes-related Impairment of Ischemia-mediated Neovascularization With Fenofibrate Treatment : Fascinating stuff from our colleagues Tony Keech, et al from down under.

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Short course oral antibiotics as good as long-course for bone infection?

November 29, 2014

Here’s a great summary and commentary regarding the work by Tone, et al that we previously posted featuring our SALSAmigos Warren S. Joseph and Mark Kosinski.  By Miriam E.

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Creating a "Hot Foot Line" Foot Hotline for Rapid Emergency Department Referrals #FootAttack

November 28, 2014
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Wireless-Powered Implantable Chip Treats Staph Infections, Dissolves Once Done

November 27, 2014

Via MedGadget! Staph infections are often localized in the body, yet can be very difficult to treat both invasively and using antibiotics.

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