Local neuroimmune impairment and the diabetic foot

Relationship between local neuroimmune impairment and diabetic foot: the immunocompromised district theory Adone Baroni, Teresa Russo, Vincenzo Piccolo International Journal of Dermatology; Early View Quote: Background Diabetic foot (DF) can be defined as an infection and/or an ulceration with or without destruction of deep tissues associated with neurological abnormalities and varying degrees of peripheral vascular disease of the lower limb in patients with diabetes. Both neuropathy and vascular disease, along with the well-known impairment of immune function in patients with diabetes, contribute to polymicrobial foot infections, which further aggravate the already severe clinical manifestations of diabetes

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Local neuroimmune impairment and the diabetic foot

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