Role of kinins in diabetic wound healing

Role of kinins in diabetic wound healing Dorinne Desposito, Catherine Chollet, Christopher Taveau, Ronan Roussel, Francois Alhenc-Gelas, Nadine Bouby, Ludovic Waeckel Archives of Cardiovascular Diseases Supplements; Volume 6, Supplement 1, April 2014, Pages 51 Quote: The diabetic foot is associated with pain, decrease in patient’s quality of life, considerable costs, and amputation. In this study, we determined the role of KKS, via activation of bradykinin receptors (B1R or B2R), in a mouse model of diabetic wound healing. Diabetic or nondiabetic mice are wounded with an 8-mm punch biopsy and then are treated or not with specific B1R or B2R agonists (720nmol/kg.d-1) and/or B2R antagonist (Icatibant, 500μg/kg.dg/d-1)

More:
Role of kinins in diabetic wound healing

Previous post:

Next post: