icaac-review-ii

News Story About Pharma Industry Payments – Response

March 13, 2013

I am sorry that it has been so long since I put up a post.  Things have been slightly hectic. Unfortunately, instead of reporting on new infectious disease information, with this entry I find myself responding to a story about my receiving payments to lecture from the pharmaceutical industry.  The story ran today (3/13/13) in the Philadelphia Inquirer and online at www.philly.com .  http://www.philly.com/philly/health/20130312_Philly_foot_doc_among_highest_paid_by_Big_Pharma.html When the original print story was run I had not had a chance to respond to the author, reporter Sam Woods.  I give Mr. Woods credit for updating the online story in response to some of my comments, reproduced below, which I emailed to him this morning.   I feel that the Pharma Industry has done an excellent job in disseminating important information that may otherwise not be available to those of us interested in saving limbs of patients with diabetes.  This is done in an unbiased, government approved and monitored way, under strict federal guidance.  My lectures are randomly, and independently audited for compliance with these guidelines and I have never been found to be deficient.  Here is my response to Mr

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New 2012 IDSA Diabetic Foot Infection Guidelines

May 22, 2012

As promised, I would post a link to the newly revised, updated IDSA DFI Guidelines as soon as they were available.  Well, I am honored, proud and excited to be able to let my readership know that after about 6 years in writing, multiple levels of peer review and well over 60 individual review comments, that the newly revised guidelines have been posted by IDSA on their website. Here is the link:    http://www.idsociety.org/uploadedFiles/IDSA/Guidelines-Patient_Care/PDF_Library/2012%20Diabetic%20Foot%20Infections%20Guideline.pdf Those of you familiar with the 2004 document will immediately notice the changes.  All IDSA Guidelines are now standardized to a “question, recommendation, evidence summary” format.  Each committee is assigned to determine which are the most critical questions that need to be answered.  In this case, we came up with 10 questions that cover everything from diagnosis to antibiotics, to osteomyelitis and wound care.  There are 44 evidenced based recommendations that  guide the clinician in the answers to those 10 questions.  The evidence is then summarized and graded by the British Medical Journal “GRADE” system.  This common sense approach matches the strength of the recommendation with the level of the evidence.  This is given in plain English.  For example “Strong, Low” means that there is a strong recommendation but a relatively low level of evidence on which the decision has been based. I hope that you all find the new Guidelines helpful in your management of these patients.  I look forward to your comments

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Antibiotic Bone Penetration and Osteomyelitis

April 2, 2012

A reader of this site, Dr. Steven Klein, emailed me to ask the following questions.  I have obtained his permission to use his excellent thoughts as a “jumping off” point for this post and some subsequent ones to follow: You recently posted about the article:  ”Systemic Antibiotic Therapy for Chronic Oysteomyelitiis in Adults.” Spellberg, Brad and Lipsky, BA

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Antibiotic Prescribing in Podiatric Medicine

January 24, 2012

I recently came across some fascinating data which breaks down the number of outpatient prescriptions written by podiatrists for all different classes of drug in 2010.  Unlike various surveys that have been done over the years by different magazines, this is hard data based on the actual number of scripts.  I would like to comment on some findings I find interesting in the use of antibiotics.  Antibiotics were the third most commonly prescribed class of drug following narcotic analgesics and NSAIDs with over 1.6 million scripts written.  This is followed closely by antifungals at about 1.4 mil prescriptions.

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SCIP Surgical Prophylaxis?

November 13, 2011

One of the most frequent questions I am used to be asked is about when antibiotic prophylaxis should be used in performing foot and ankle surgery.  I have an entire lecture on this topic where I go through the data, or lack thereof, on the subject and suggest the clinical situations where prophy has traditionally been utilized (i.e. surgery longer than 2 hours, trauma surgery, immunocompromised hosts, etc).  More and more the question posed to me has become: “Warren, my hospital requires me to use prophylactic antibiotics even when I don’t feel they are necessary.  They have actually threatened to take away my surgical privileges if I don’t use them.  What can I do about that?”  Unfortunately, the answer is… not much

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Literature Update – Antimicrobial Agents and Chemotherapy, Sept, 2011

September 7, 2011

As I have mentioned in a previous post there are a number of journals I follow to stay abreast of developments in the ID, microbiology and antibiotic world.  For updates on the latest in antibiotic development from pre-clinical through clinical testing no journal beats the American Society of Microbiology’s Antimicrobial Agents and Chemotherapy (http://asm.org/).  Just to give a taste of how relevant this publication can be to those of us treating lower extremity infections, in the current September 2011 issue of AAC there at least 5 papers that present useful information.  In this “Literature Update” I will list these manuscripts, give the PubMed link to their Abstracts, and give a summary of what the authors reported.

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Infection Control and Instrument Disinfection

July 25, 2011

This week I will be giving a talk to the Podiatric Assistants at the APMA National Meeting in Boston on the topic of office infection control.  I believe that this is an area which does not receive enough attention since it is far from “sexy” or cutting edge but is still important.  Last year I sat in on discussions by the Clinical Practices Committee of The American Podiatric Medical Association in an attempt to come up with some Guidelines for disinfection and sterilization of instruments for the podiatric physician.  This document, available online for members of APMA by searching the term “disinfection” in the Members Section at www.apma.org , incorporates information from the CDC document “ Guidelines for Disinfection and Sterilization in Healthcare Facilities, 2008 ” also available online at http://www.cdc.gov/hicpac/pdf/guidelines/Disinfection_Nov_2008.pdf .  Much of the CDC document is not directly applicable to daily office practice, thus the need for the specialized Guidelines.  In the APMA document we approached podiatric instrumentation much the same way as the dentist classify their instruments.  They are broken down into 3 categories: Critical Instruments : These are any object that enters sterile tissue or the vascular system and therefore must be sterile because any contamination could transmit disease.  These would include any instrument used in a surgical procedure.  These instruments should be sterilized. Semi-critical Instruments : These instruments contact non intact skin.  Examples would include tissue nippers or curettes used in debridement of an ulceration or incision and drainage of an abscess.  These devices require high level disinfection. Noncritical Instruments : These come in contact with intact skin or nails.

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Bugs and Drugs 2011 (Slide Show)

May 3, 2011

With this entry onto the blog I am trying something new.  The IT team at Data Trace has been working on a way to post a PowerPoint slide show to the blog.  We believe it is now ready to go.  For this first PowerPoint, I am posting the lecture I gave at DFCON 2011 in Hollywood, CA back in late March.  The topic is “Bugs and Drugs 2011″.  As sometimes happens at that excellent meeting, I did not have enough time to go through the entire talk so, even back then, I offered to put the lecture up on my blog for viewing.  I hope you find the information on the slides interesting and informative.  If you have any questions about any content or see a subject on which you would like me to expound on this site, please let me know.

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What Would You Do? – Imaging for Osteomyelitis

April 25, 2011

It has been a little while since I asked a clinical question of you, the readers.  I actually received a pretty good response last time and some interesting thoughts so I figured I would post a question that was recently asked of me:  “What is your opinion on the ‘standard of care’ of the need for serial imaging (x-rays in particular but also possibly MRI or nuclear scans can be considered) in a chronic plantar wound, in a patient with diabetes?  The wound does not probe and there are no signs of clinical infection.  The wound is probably not healing because of non-adherence with off loading instructions. How often would you order the different imaging studies?” The reason I am bringing this up to you is that I think it is a really interesting question.  What do you think?  Please respond and let me know.  After I hear from you, I will try to give you my thoughts on it.

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THE 80% SOLUTION (With apologies to Sir Arthur Conan Doyle)

February 24, 2011

This Tuesday, February 22, I was quoted in a very fair and balanced article in the Wall Street Journal by Science Reporter Laura Johannes dealing with laser treatment of onychomycosis . During my interview with Ms

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